Wednesday 8 April 2015

Customizing Your Study by Choosing Tissue Array from Creative Bioarray



Tissue arrays, or tissue microarrays (TMAs), are usually produced by a method of re-locating tissue from conventional histologic paraffin blocks. Through TMAs, researchers get an example of what a tissue microarray and its construction is, as well as knowing what are the completed colon cancer array and spots from this array and a melanoma array.

All of this can be achieved by a hollow needle, which is used to biopsy a standard histologic sections and placing the core (which is as small as 0.6 mm in diameter) into an array on a recipient paraffin block.

As early as 28 years ago, this technique has been described by two people named Wan, Fortuna, and Furmanski, who put forward their ideas in Journal of Immunological Methods. However, the TMAs technique was actually popularized after a publication in Nature Medicine in 1998, written by Kononen and colleagues in the laboratory of Ollie Kallioneimi.

Nowadays, Tissuemicroarrays (TMAs) provide research communities a means for rapid, large-scale analysis of several hundred tissue specimens. 

This High-throughput genome screening technology has also made it possible to survey thousands of genes at a time from tissues and cells. There was no doubting that the translation of such information to improve diagnostic, prognostic and therapeutic applications requires extensive validation.

Creative Bioarray’s tissue arrays help scientists and researchers efficiently analyze gene and protein expressions in multiple tissue samples. We can provide you this high-throughput technique---TMAs, which allows rapid gene expression and copy-number surveys of large numbers of different tissue specimens.

Moreover, based on the availability of more than 500,000 human and 30,000 animal samples in our tissue bank, we have the ability to construct high quality tissue arrays to satisfy your special requirements.

Besides, we have also established standard operation procedure in custom array service. Our tissue microarrays are produced by re-locating tissues from conventional histological blocks. Typically, 40 to 1,000 cylindrical formalin-fixed and paraffin-embedded tissue cores can be densely and precisely arrayed into a single paraffin block. From the block, up to 300 serial 4-8 μm thick sections can be produced and placed on individual glass microscopic slides.

With our professional support and technique, you can have all your required Custom Tissue Array provided by us Creative Bioarray. So, please don't hesitate to call us at 1-631-626-9181 or email to info@creative-bioarray.com for further details.

1 comment:

  1. We are very interested in your tissue array services and hope to have a further cooperation.

    CA

    ReplyDelete